Profhilo London is one of the most searched-for injectable skin treatments in the UK right now — and at Rejuva London on Harley Street, it is also one of our most-requested procedures. Unlike dermal fillers that add volume, Profhilo is a bio-remodelling agent made from ultra-pure hyaluronic acid that spreads beneath the skin to stimulate collagen and elastin from within. The result is visibly healthier, more radiant skin — without changing how you look.
What Is Profhilo?
Profhilo is a next-generation injectable treatment developed by IBSA using their patented NAHYCO® technology. It contains one of the highest concentrations of pure hyaluronic acid available in any injectable product (64mg/2ml), but it is not a filler. Instead of sitting in one place, it flows through the skin tissue, hydrating deeply and triggering the body’s natural repair process — stimulating four types of collagen and elastin simultaneously.
The BAP (Bio Aesthetic Points) technique used at Rejuva London involves just ten injection points across the face, making the procedure quick, precise, and comfortable. Sessions typically take 30 minutes from start to finish.
Profhilo Before and After: What Results Can You Expect?
Most clients notice a visible difference within two to four weeks of their first Profhilo session in London. After completing the full two-session course — spaced four weeks apart — the results become significantly more pronounced:
- Deep hydration: Skin feels plumper, softer, and consistently moisturised — even through London’s harsh winters and air-conditioned summers.
- Improved firmness and elasticity: The collagen and elastin stimulation rebuilds the skin’s internal scaffolding, so skin feels bouncier and looks tighter over time.
- Natural glow: Dull, tired-looking skin regains luminosity. Many clients describe their skin as looking “refreshed” or “well-rested” rather than done.
- Softened fine lines: As skin quality improves, fine lines around the eyes, mouth and neck become less noticeable without any structural change.
Results from a full Profhilo course typically last around six months. A single maintenance session every six to twelve months keeps the benefits ongoing.
How Much Does Profhilo Cost in London?
Profhilo cost in London varies depending on the clinic’s location, the practitioner’s credentials, and the treatment area. Here is a general guide for 2026:
| Treatment Area | Price Per Session | Full Course (2 Sessions) |
|---|---|---|
| Face | £350–£450 | £700–£900 |
| Face + Neck | £450–£550 | £900–£1,100 |
| Face + Neck + Décolletage | £550–£700 | £1,100–£1,400 |
At Rejuva London, all Profhilo treatments are performed by qualified doctors at our Harley Street clinic. We recommend beginning with a consultation to determine the right treatment area and course for your skin goals.
Profhilo vs Skin Boosters: Which Is Right for You?
In 2026, one of the most common questions we receive is: “What’s the difference between Profhilo and a skin booster?” They are not the same thing, and the distinction matters.
| Profhilo | Skin Boosters (e.g. Restylane, SKINVIVE) | |
|---|---|---|
| How it works | Bio-remodels skin via collagen & elastin stimulation | Delivers hyaluronic acid directly into dermis for hydration |
| Injection points | 10 BAP points | 30–60+ micro-injections |
| Results timeline | 4–8 weeks (collagen build-up) | 1–2 weeks (immediate glow) |
| Best for | Skin quality, firmness, laxity | Surface hydration, texture, fine lines |
| Duration | ~6 months | ~6 months |
Choose Profhilo if: your skin feels lax, dull, or has lost its bounce — and you want a deep, lasting structural improvement. Choose a skin booster if: your main concern is surface texture, dryness, or you want an instant dewy glow. Many clients at Rejuva London combine both — your doctor can advise on the best sequencing during your consultation.
What Happens During Your Profhilo Treatment at Rejuva London?
Step 1 — Consultation: Your doctor assesses your skin, discusses your concerns, and confirms Profhilo is appropriate for your goals.
Step 2 — Preparation: The skin is cleansed and, if preferred, a topical anaesthetic cream is applied.
Step 3 — BAP injections: Ten precise injections are made at anatomically selected points across the face. The product spreads naturally beneath the skin. The process takes 15–20 minutes.
Step 4 — Aftercare: Mild redness or small bumps at injection sites are normal and typically resolve within 24–48 hours. Full aftercare instructions are provided.
Step 5 — Second session (four weeks later): The second session consolidates the collagen-stimulating process and delivers the full benefit.
Who Is Profhilo Suitable For?
- Are in your 30s, 40s or 50s and have noticed your skin losing bounce and luminosity
- Want to improve skin quality without changing your features — no added volume, no altered contours
- Are new to aesthetic medicine and looking for a natural, gentle entry point
- Already have anti-wrinkle injections or fillers and want to improve overall skin health
- Have dry, dull or slightly lax skin that is not responding to skincare alone
Why Choose Rejuva London for Profhilo?
Doctor-led treatments only: All Profhilo injections at our Harley Street clinic are performed by qualified doctors — never delegated to non-medical practitioners. Authentic IBSA Profhilo: We use exclusively original Profhilo product. Personalised treatment plans: Your doctor will assess your skin in depth and recommend the programme best suited to your goals. Harley Street location: 15 Harley Street, Marylebone, W1G 9QQ.
Frequently Asked Questions
What is the difference between Profhilo and a dermal filler?
Dermal fillers add volume or redefine contours — for example, plumped lips or restored cheekbones. Profhilo does neither. Instead, it spreads through the skin to stimulate collagen and elastin production, improving skin quality, hydration and firmness without adding bulk or changing your facial structure.
How long does it take to see Profhilo results?
Most clients notice initial improvements in skin hydration within two to four weeks of their first session. The full collagen-stimulating effect develops after the second session, with results continuing to improve over the following weeks.
Is Profhilo painful?
Most clients find the treatment very tolerable. The BAP technique uses only ten injection points and topical anaesthetic cream is available on request. Any discomfort is typically brief and mild.
How long do Profhilo results last?
A full course of two sessions typically delivers results lasting around six months. A single maintenance session every six to twelve months is usually sufficient to sustain the improvement long-term.
Can I combine Profhilo with other treatments?
Yes — Profhilo pairs very well with anti-wrinkle injections, dermal fillers, and skin boosters, as it targets a different aspect of skin health: quality rather than volume or movement. Your doctor will advise on the ideal sequencing and timing.
How much does Profhilo cost at Rejuva London?
Profhilo pricing at Rejuva London varies depending on the treatment area. Please book a consultation for a personalised quote.
Book Your Profhilo Consultation in London
📍 Rejuva London — 15 Harley Street, London W1G 9QQ | 🚇 Nearest tube: Regent’s Park



