Meta description (155 chars): SKINVIVE vs Profhilo London: doctor-led guide on cost, results, longevity and which skin booster suits your skin in 2026. Book at Rejuva London Harley Street.
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If you have been researching SKINVIVE vs Profhilo London, you are probably asking the same question we hear in clinic every week: which skin booster actually delivers, and which one is right for your skin? At Rejuva London on Harley Street, our doctors offer both treatments because they solve different problems — and choosing well is the difference between glow that fades in eight weeks and a year of skin that genuinely looks healthier.
This 2026 guide explains the real differences between SKINVIVE® by JUVÉDERM® and Profhilo®, what each costs in London, how long results last, and why combining them is increasingly the doctor-led choice for clients in their 30s, 40s and 50s.
What Is a Skin Booster, and Why the Hype?
A skin booster is an injectable hyaluronic acid (HA) treatment that improves the quality of your skin — hydration, elasticity, smoothness and that lit-from-within glow — without changing your facial volume the way a filler would. Skin boosters sit in a category of their own: not a wrinkle injection, not a contouring filler, but a treatment focused on skin biology.
In the UK market, two names dominate the conversation in 2026: SKINVIVE and Profhilo. Both are HA-based, both are administered by injection, and both promise better-looking skin. The similarities largely end there.
What Is SKINVIVE by JUVÉDERM?
SKINVIVE is the first FDA-approved injectable HA microdroplet skin booster, developed by Allergan Aesthetics. It uses a cross-linked HA technology delivered as small, precise micro-droplets just beneath the surface of the skin, typically in the cheek area.
Because the HA is cross-linked, SKINVIVE stays where it is placed for longer than traditional skin boosters. The mechanism is simple: hydration is held in the upper layers of the skin, the surface looks smoother, fine lines soften, and the skin develops the dewy, “filtered” look that has driven so much of its popularity on social media.
A SKINVIVE treatment at Rejuva London is one session, with an optional top-up at four weeks. There is no cross-face structural change — your face shape stays exactly as it is.
What Is Profhilo?
Profhilo, made by IBSA, takes a fundamentally different approach. It is a high-concentration (64 mg / 2 ml) non-cross-linked pure HA, injected at five strategic Bio Aesthetic Points (BAP) on each side of the face. Once placed, Profhilo spreads through the deeper layers of the skin and triggers what manufacturers call bio-remodelling: the slow stimulation of new collagen, elastin and the body’s own HA.
This is why Profhilo is often described as “an injectable skin tightening” rather than a hydrator. The result is firmer, more elastic skin from within, particularly useful for clients showing early laxity, crepiness on the lower face, or thinning skin on the neck and décolletage.
The standard Profhilo protocol at Rejuva London is two sessions four weeks apart, with maintenance every six to nine months.
SKINVIVE vs Profhilo: The Real Differences
| Factor | SKINVIVE by JUVÉDERM | Profhilo |
|---|---|---|
| HA type | Cross-linked, microdroplet | Non-cross-linked, high-concentration |
| Layer of skin | Superficial / mid-dermis | Deeper layers, spreads broadly |
| Main action | Hydration, glow, surface smoothing | Bio-remodelling, collagen + elastin stimulation |
| Sessions | 1 (optional top-up) | 2, four weeks apart |
| Visible change in | 2–4 weeks | 30+ days |
| Lasts | Up to 6 months (some patients up to 9) | 6–12 months |
| Best for | Dull, dehydrated skin needing glow | Early laxity, crepiness, loss of firmness |
In short: SKINVIVE is the hydration treatment, Profhilo is the structural treatment. They are not direct substitutes — they target different problems in different layers of the skin.
SKINVIVE vs Profhilo: Before and After Results
What You Can Expect From SKINVIVE
After one session, most clients see a noticeable improvement in skin smoothness, light reflection and that “lit-from-within” glow within two to four weeks as the HA integrates and hydrates. Fine lines on the cheek soften. The change is real but subtle — friends often say “your skin looks great” rather than “what have you had done?”. Results plateau around six months, when a top-up is recommended.
What You Can Expect From Profhilo
Profhilo is a slower reveal. Around 30 days after the second session, the skin feels firmer and looks more elastic, particularly along the jawline, lower cheeks and neck. Crepiness reduces. Clients in their late 30s to 50s often describe it as “my skin looking like itself again, but better”. Best results last six to twelve months, then the protocol is repeated.
The key honest expectation: neither treatment is a facelift, and neither replaces wrinkle injections or fillers if those are appropriate for you.
How Much Does SKINVIVE and Profhilo Cost in London?
Pricing in 2026 across reputable London clinics generally falls in the following ranges:
- **SKINVIVE London**: £450–£650 per session (one syringe, full face)
- **Profhilo London**: £450–£600 per session, or £800–£1,150 for the full two-session course
At Rejuva London, your initial consultation with our doctors is complimentary and includes a full skin assessment so we can recommend the right protocol — not just the most expensive one. We publish current pricing transparently and will never upsell a treatment that does not fit your goals.
Can You Combine SKINVIVE and Profhilo?
Yes — and for many clients this is the most effective approach. Because SKINVIVE works on hydration and surface glow while Profhilo works on collagen and structural elasticity, the two treatments are biologically complementary rather than competing.
A typical combined protocol at Rejuva London looks like:
- **Profhilo session 1** at week 0 — set the foundation.
- **Profhilo session 2** at week 4.
- **SKINVIVE** at week 8 — layer the surface glow on top of the structural improvement.
This sequencing avoids overwhelming the skin and lets each product do its job in the right layer. Your doctor will tailor the timing based on your skin assessment.
Who Is SKINVIVE Right For?
Choose SKINVIVE if your main concerns are:
- Dull, dehydrated skin that does not respond fully to topical skincare.
- Loss of “glow” or that healthy, dewy look.
- Fine surface lines on the cheeks.
- Wanting one quick session before a wedding, holiday, milestone event, or simply a refresh.
Who Is Profhilo Right For?
Choose Profhilo if your main concerns are:
- Early skin laxity or loss of firmness.
- Crepiness on the cheeks, neck or décolletage.
- Skin that has thinned with age and feels less elastic.
- Wanting a longer-term skin quality investment with collagen-stimulating benefits.
Why Choose Rejuva London for Skin Boosters?
Rejuva London is a doctor-led aesthetic clinic on Harley Street in Marylebone, focused on long-term skin health rather than one-off promotions. Every SKINVIVE and Profhilo treatment is carried out by GMC-registered doctors who decide injection points individually for each client, not from a one-size-fits-all template.
We chose to offer both products precisely because no single skin booster suits every client. The treatment that wins for you is the one that targets the layer of your skin that needs the most help — which is what your consultation is for.
Frequently Asked Questions
What is the difference between Profhilo and SKINVIVE?
Profhilo is a non-cross-linked HA bio-remodeller that stimulates collagen and elastin in the deeper layers of the skin, improving firmness over six to twelve months. SKINVIVE is a cross-linked HA microdroplet hydrator that improves surface glow and smoothness for up to six months. Profhilo treats laxity; SKINVIVE treats hydration.
Which is better, SKINVIVE or Profhilo?
Neither is universally “better” — they treat different problems. If you want glow and hydration, SKINVIVE wins. If you want firmer, more elastic skin, Profhilo wins. Many clients use both in sequence.
How long do SKINVIVE and Profhilo results last?
SKINVIVE results last around six months, sometimes up to nine. Profhilo results last six to twelve months depending on age, skin type and lifestyle. Both are maintenance treatments rather than permanent fixes.
Can SKINVIVE and Profhilo be safely combined?
Yes. They work in different skin layers and are commonly combined under a doctor’s protocol — typically Profhilo first, SKINVIVE four weeks after the second Profhilo session.
How much does SKINVIVE cost in London?
At reputable doctor-led clinics in London in 2026, SKINVIVE typically costs £450–£650 per session. Always confirm what is included — some clinics quote per syringe and add a consultation fee.
Is there any downtime?
Both treatments are walk-in, walk-out. You may have small injection-point bumps for a few hours (Profhilo) or up to 24–48 hours (SKINVIVE). Most clients return to work the same day with light makeup.
Book Your Skin Booster Consultation
If you are still unsure whether SKINVIVE, Profhilo, or both is right for your skin, book a complimentary consultation with our doctors at Rejuva London on Harley Street. We will assess your skin, walk you through the realistic results for each treatment, and only recommend what genuinely fits your goals.
