Rejuva London Harley Street
Rejuva London Harley Street
frown lines treatment 11s botox london

Frown Lines Treatment London: Eliminate 11s Between Eyebrows

Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Please consult with a qualified medical professional for personalized assessment and treatment recommendations.

Medical Review: This article has been medically reviewed and approved by Dr. Kristy Lau.

Dec 24, 2025

Dec 24, 2025

Frown Lines Treatment: Expert Solutions for a Refreshed, Natural Appearance

Those persistent ’11 lines’ between your eyebrows can significantly impact both your appearance and confidence. Beyond making you look angry or worried when you’re not, deep frown lines can add years to your face and create a permanently tired or stressed expression that doesn’t reflect how you truly feel.

At Rejuva London, we offer advanced, doctor-led treatments specifically tailored to address glabellar lines at every stage of development. From preventative approaches using precisely placed anti-wrinkle injections to comprehensive combination therapies for deeper, established lines, our treatments deliver noticeable yet natural results without the frozen appearance many patients fear.

Treatment sessions typically take just 15-30 minutes with minimal to no downtime, allowing you to return to your daily activities immediately. Most patients notice significant improvement within 3-14 days, with results lasting 3-6 months depending on the treatment approach selected for your specific needs.

As a medical doctor with over 30 years’ experience, I personally perform all injectable treatments, ensuring the highest standards of safety and aesthetic excellence. My approach focuses on refreshing your appearance while maintaining natural expressiveness – you’ll still look like yourself, just more rested and rejuvenated.

If you’re concerned about frown lines affecting your appearance, book a one-to-one consultation at our Harley Street clinic to discover the most appropriate treatment options for your unique facial anatomy and aesthetic goals.

Table of Contents

Understanding Frown Lines: What Causes 11 Lines Between Eyebrows

As a doctor with over 30 years of medical experience, I’ve treated thousands of patients concerned about those persistent vertical lines between their eyebrows. These ’11 lines’ (named for their resemblance to the number 11) or glabellar lines are among the most common cosmetic concerns I address at our Harley Street clinic.

Frown lines develop primarily due to repeated muscle contractions. The glabellar region contains several muscles, including the corrugator supercilii and procerus muscles, which contract when we concentrate, squint, or express negative emotions like frustration or anger. Think of these muscles like elastic bands – with repeated stretching over time, they begin to create visible creases in the skin above.

Several factors contribute to the formation of these lines:

  • Facial expressions: Frequent frowning, squinting, or concentrating
  • Sun exposure: UV damage breaks down collagen and elastin
  • Natural ageing: Decreased skin elasticity and collagen production
  • Genetics: Some people are predisposed to developing deeper lines
  • Lifestyle factors: Smoking, poor hydration, and inadequate skincare

What makes these lines particularly bothersome is their tendency to create an appearance of anger, worry, or fatigue – even when you’re feeling perfectly content. Many of my London patients report that colleagues ask if they’re upset when they’re simply concentrating, which can affect both professional and personal interactions.

Why Do Glabellar Lines Deepen Over Time?

In my clinical experience at Rejuva London, I’ve observed that glabellar lines typically begin as dynamic wrinkles – appearing only during facial movement – but gradually transform into static wrinkles that remain visible even when your face is at rest. This progression isn’t simply about getting older; it’s a complex interplay of factors that accelerate the deepening of these lines.

The primary reason glabellar lines worsen over time is the cumulative effect of repeated muscle contractions. Each time you frown, squint, or concentrate intensely, the corrugator and procerus muscles contract, creating temporary creases. Over decades, these repeated movements essentially “train” the skin to fold along these lines, much like creasing paper in the same place repeatedly.

Simultaneously, several age-related changes contribute to deeper frown lines:

  • Collagen and elastin depletion: These structural proteins decline by approximately 1% annually after age 20, reducing skin’s ability to bounce back from creasing
  • Decreased hyaluronic acid: Natural skin hydration diminishes, making the skin less plump and more prone to settling into creases
  • Bone resorption: Subtle changes in facial bone structure can affect the support framework for skin and muscles
  • Fat redistribution: Loss of facial fat volume can make existing lines appear more pronounced

Environmental factors significantly accelerate this process. In London’s urban environment, exposure to pollution, UV radiation (even on cloudy days), and lifestyle stressors can dramatically hasten the breakdown of skin’s supportive structures, deepening these troublesome 11 lines between the eyebrows.

Preventing Frown Lines: Can You Stop Expression Lines Forming?

As I often explain to my patients at our Harley Street clinic, while we cannot completely prevent expression lines (nor would we want to eliminate all facial expressions!), we can certainly take proactive steps to minimise their development and depth. Prevention is always more effective than correction when it comes to frown lines.

The most effective preventative strategies I recommend include:

  • Sun protection: Daily SPF 30-50 application is non-negotiable, even in London’s cloudy weather. UV damage accelerates collagen breakdown, making it the number one preventable cause of premature skin ageing.
  • Facial awareness: Simply becoming conscious of habitual frowning can help reduce unnecessary muscle contractions. Many patients benefit from setting periodic reminders to check if they’re tensing their forehead muscles while working.
  • Comprehensive skincare: A regimen including antioxidants (vitamin C serum in the morning), retinoids (in the evening), and hydrating ingredients (hyaluronic acid, ceramides) helps maintain skin resilience.
  • Preventative treatments: For patients in their late 20s to early 30s, we offer “baby Botox” – smaller doses of anti-wrinkle injections that prevent deep line formation while maintaining natural expression.
  • Lifestyle modifications: Adequate hydration, balanced nutrition rich in antioxidants, sufficient sleep, and stress management all contribute to healthier skin that resists wrinkling.

In my 30+ years of medical experience, I’ve observed that patients who implement these preventative measures consistently show significantly slower progression of glabellar lines compared to those who don’t. At Rejuva London, our doctor-led approach means we can create personalised prevention strategies based on your unique facial anatomy, muscle strength, and skin condition.

Top Frown Lines Treatments Available in London

At Rejuva London, I offer a comprehensive range of doctor-led treatments specifically designed to address frown lines. Based on treating over 20,000 patients since we opened our Harley Street clinic, I’ve refined our approach to provide options suitable for every stage of glabellar line development.

TreatmentBest ForResults TimelineDowntime
Anti-wrinkle Injections (Botox)Dynamic lines, prevention, mild to moderate static lines3-5 days initial, 14 days full resultsNone to minimal
Dermal FillersDeep, etched-in static linesImmediate with refinement over 2 weeksMinimal (possible bruising)
UltherapySkin laxity contributing to frown appearance2-3 months for full resultsNone to minimal
PicoSure Pro LaserSkin texture and superficial linesProgressive improvement over 4-6 weeks1-2 days redness
Combination TherapyComplex cases with multiple contributing factorsVaries by protocolVaries by protocol

What distinguishes our approach at Rejuva London is our commitment to doctor-led treatments. Unlike many London clinics where treatments are delegated to non-medical practitioners, I personally perform all injectable and advanced treatments. This medical expertise allows me to assess the complex interplay between your facial muscles, skin quality, and underlying structures to recommend the most effective treatment pathway.

For most patients with frown lines, we begin with precisely placed anti-wrinkle injections to relax the underlying muscles, often complemented by targeted skincare to improve skin quality. For deeper, more established lines, we may recommend a combination approach that addresses both muscle activity and skin texture simultaneously.

Botox for Frown Lines: Procedure, Units Required & Results

As a doctor with extensive experience in facial aesthetics, I consider anti-wrinkle injections (commonly known as Botox) the gold standard for treating glabellar frown lines. At Rejuva London, I personally perform all injectable treatments, ensuring the highest level of precision and safety for our Harley Street patients.

The procedure itself is straightforward but requires expert anatomical knowledge. During your treatment:

  1. I begin with a detailed facial assessment, observing how your specific muscles contract when you frown
  2. The glabellar area is cleansed thoroughly
  3. Using an ultra-fine needle, I precisely inject the product into 5-7 strategic points targeting the corrugator and procerus muscles
  4. The entire procedure takes approximately 15-20 minutes, with the injections themselves lasting only a few minutes

The number of units required varies based on individual factors including muscle strength, gender, and the depth of existing lines. Typically:

  • Women generally require 15-25 units for the glabellar region
  • Men often need 20-30 units due to stronger muscle mass
  • First-time patients may start with a conservative dose, with refinement at a 2-week review
  • Preventative treatments for younger patients might use 10-15 units

Results develop gradually: you’ll notice initial changes within 3-5 days, with full results visible by day 14. The transformation is remarkable yet natural – the deep “11s” soften significantly, creating a more relaxed, approachable appearance without affecting your ability to express emotions. Proper aftercare is essential for optimal results, which is why we provide comprehensive guidance following your treatment.

What truly sets our approach apart is the doctor-led precision. Rather than a one-size-fits-all application, I carefully assess your unique facial anatomy and customize the injection pattern to ensure natural movement while effectively addressing the frown lines.

Beyond Botox: Alternative Treatments for Deep Glabellar Lines

While anti-wrinkle injections remain the first-line treatment for most frown lines, I find that patients with deeper, more established glabellar lines often benefit from a multi-modal approach. At our Harley Street clinic, I offer several advanced alternatives that can be used either as standalone treatments or in strategic combination with Botox.

For deeply etched static lines that remain visible even when muscles are relaxed, I often recommend:

  • Dermal Fillers: Using ultra-fine hyaluronic acid fillers specifically designed for superficial lines, I can carefully fill the depression of deep glabellar lines. This provides immediate structural support and stimulates collagen production over time. The technique requires exceptional precision to avoid complications in this vascular area.
  • Skin Resurfacing: Our PicoSure Pro laser technology stimulates deep collagen remodelling without damaging the skin’s surface. This is particularly effective for improving skin texture around glabellar lines and can enhance the results of injectable treatments.
  • Ultherapy: This focused ultrasound technology delivers energy to the deeper structural layers of the skin, stimulating new collagen production. For patients with skin laxity contributing to their frown appearance, this non-invasive treatment provides gradual, natural-looking improvement.
  • Platelet-Rich Plasma (PRP): Using growth factors from your own blood, this treatment stimulates cellular renewal and collagen production. I often recommend this for patients seeking completely natural approaches to skin rejuvenation.

The most effective approach for severe glabellar lines is typically a customised combination protocol. For instance, I might recommend initial Botox to relax the muscles, followed by targeted filler placement once the muscles are immobilised, and complemented by a course of collagen-stimulating treatments to improve skin quality over time.

As a doctor with over 30 years of medical experience, I carefully assess each patient’s unique facial anatomy, skin condition, and aesthetic goals to determine which combination will provide optimal, natural-looking results for their specific type of frown lines.

How Long Do Frown Line Treatments Last?

One of the most common questions my patients ask at our Harley Street clinic concerns the longevity of frown line treatments. Based on treating over 20,000 clients at Rejuva London, I can provide detailed insights into what you can realistically expect.

The duration of results varies by treatment type and individual factors:

TreatmentAverage DurationInfluencing Factors
Anti-wrinkle Injections3-4 months initially, potentially longer with regular treatmentsMetabolism, muscle strength, dosage, treatment frequency
Dermal Fillers6-12 monthsFiller type, injection depth, area mobility, metabolism
Ultherapy12-18 monthsAge, skin condition, lifestyle factors
PicoSure Pro LaserResults continue to improve for 6+ months after treatment seriesNumber of sessions, skin type, sun protection adherence

Interestingly, I’ve observed that patients who maintain regular treatment schedules often experience increasing longevity over time. For example, while initial Botox treatments typically last 3-4 months, patients who receive treatments 3-4 times annually often find their results extending to 4-6 months after the first year. This occurs because the targeted muscles gradually weaken with consistent treatment, requiring less frequent maintenance.

To maximise the longevity of your frown line treatments, I recommend:

  • Following a comprehensive skincare regimen with SPF, antioxidants, and retinoids
  • Maintaining consistent treatment intervals rather than waiting until lines fully return
  • Combining treatment modalities for synergistic, longer-lasting results
  • Addressing lifestyle factors that accelerate ageing (smoking, excessive sun exposure, poor hydration)

At Rejuva London, our doctor-led approach means I personally track your treatment response over time, allowing me to refine your protocol for optimal longevity while maintaining natural-looking results.

Why Choose Rejuva London for Your Frown Line Treatment

When it comes to treating delicate areas like the glabellar region, medical expertise makes all the difference. As an Imperial College London graduate with over 30 years of medical experience, I established Rejuva London with a fundamental commitment: all injectable and laser treatments are exclusively doctor-led – a policy that sets us apart from many other London clinics.

Choosing Rejuva London for your frown line treatment means benefiting from:

  • Medical Excellence: As a GMC registered doctor, I bring comprehensive anatomical knowledge and injection precision that ensures both safety and optimal aesthetic outcomes.
  • Personalised Approach: No two faces are identical. I personally assess each patient’s unique muscle patterns, skin quality, and facial proportions to create bespoke treatment plans that address your specific type of frown lines.
  • Advanced Technology: Our Harley Street clinic is equipped with cutting-edge technologies including PicoSure Pro, Thermage, and Ultherapy – allowing us to offer comprehensive solutions beyond basic injectables.
  • Natural Results Philosophy: We specialise in refreshed, natural-looking outcomes that enhance your appearance without obvious signs of treatment. My patients consistently report colleagues noticing they look “well-rested” rather than “treated.”
  • Proven Track Record: Having successfully treated over 20,000 patients since 2018, our expertise in addressing frown lines is well-established and refined.

Our prestigious 15 Harley Street location provides a discreet, clinical environment where your treatment is performed to the highest medical standards. Following your procedure, you’ll receive comprehensive aftercare guidance and a personal follow-up to ensure optimal results.

I believe that aesthetic treatments should be approached with the same medical rigour as any healthcare procedure. This doctor-led philosophy ensures that when you choose Rejuva London for your frown line treatment, you’re receiving care from a practitioner who understands not just the aesthetics, but the complex anatomy and physiology behind creating natural, harmonious results.

To discuss how we can help address your frown lines with a personalised treatment plan, I invite you to book a consultation at our Harley Street clinic. Together, we’ll create a bespoke approach to help you achieve a naturally refreshed appearance.

Frequently Asked Questions

How do you get rid of frown lines permanently?

While no treatment can permanently eliminate frown lines, long-term reduction is possible through a combination of approaches. Anti-wrinkle injections (Botox) provide temporary relaxation of the muscles causing frown lines for 3-4 months. For more lasting results, I often recommend a multi-modal approach including dermal fillers to restore volume, energy-based treatments like Ultherapy to stimulate collagen production, and consistent skincare with retinoids and SPF. Surgical options like brow lifts can provide more permanent correction for severe cases, but all treatments require maintenance to sustain results as the ageing process continues.

How many units of Botox are needed for frown lines?

Most patients require 15-25 units of Botox for effective treatment of frown lines. Women typically need 15-20 units, while men often require 20-30 units due to stronger glabellar muscles. The exact amount varies based on several factors:

  • Muscle strength and size
  • Depth of existing lines
  • Previous treatment history
  • Desired level of movement retention
  • Gender (men typically require more units)

At Rejuva London, I personally assess each patient’s unique facial anatomy to determine the precise dosage needed for natural-looking results.

Can frown lines be prevented?

Yes, frown lines can be significantly prevented or delayed with proactive measures. The most effective prevention strategy includes consistent sun protection with SPF 30-50 daily, even in cloudy London weather. Early preventative “baby Botox” treatments starting in your late 20s or early 30s can train muscles to contract less forcefully before deep lines form. Additionally, a comprehensive skincare routine with retinoids, antioxidants, and hydrating ingredients helps maintain skin elasticity. Becoming aware of habitual frowning and managing stress also reduces the repetitive muscle contractions that eventually create permanent lines.

What causes deep frown lines between eyebrows?

Deep frown lines (glabellar lines) primarily develop from repeated muscle contractions of the corrugator supercilii and procerus muscles when frowning, concentrating, or squinting. These repetitive movements, combined with age-related collagen loss of approximately 1% annually after age 20, gradually create permanent creases. Contributing factors include:

  • UV exposure breaking down skin’s supportive structures
  • Genetic predisposition to stronger facial muscles or thinner skin
  • Hormonal changes affecting skin elasticity
  • Lifestyle factors like smoking, poor hydration, and stress
  • Sleeping positions that compress facial skin

The depth of these “11 lines” typically increases with age as skin loses its natural ability to bounce back from repeated creasing.

How long do frown line treatments last?

The longevity of frown line treatments varies by method and individual factors. Anti-wrinkle injections (Botox) typically last 3-4 months initially, with duration often extending to 4-6 months after regular treatments as muscles gradually weaken. Dermal fillers for deep static lines generally last 6-12 months, while collagen-stimulating treatments like Ultherapy can provide improvements for 12-18 months. Factors affecting longevity include your metabolism, muscle strength, lifestyle factors, and treatment frequency. At Rejuva London, I’ve observed that patients following a consistent treatment schedule and proper skincare maintenance achieve the most enduring results.

Dr. Kristy Lau, Medical Director of Rejuva London

Dr. Kristy Lau

Medical Director & Founder

Aesthetic Clinic London

MBBS Imperial College London
GMC Registered
30+ Years Medical Experience

Dr. Kristy Lau is the founder and Medical Director of

Rejuva London Clinic
, an

Imperial College London

graduate with over 10 years of comprehensive medical expertise. Specializing in dermatology and medical aesthetics, Dr. Lau combines rigorous medical training with advanced aesthetic technologies to deliver personalized, natural-looking treatments.

At Rejuva London’s prestigious Harley Street location, Dr. Lau ensures all procedures are performed exclusively by highly experienced doctors, maintaining the highest standards of safety and excellence in aesthetic medicine. Her doctor-led approach has successfully treated over 20,000 clients since establishing the clinic in 2018.

Medical Specializations:

Injectable Treatments
  • Anti-wrinkle Injections (Botox)
  • Dermal Fillers
  • Facial Contouring
Advanced Technologies
  • Picosure Pro Laser
  • Thermage RF
  • Ultherapy
Medical Dermatology
  • Skin Health Assessment
  • Medical Aesthetics
  • Laser Skin Treatments

Professional Qualifications & Credentials:

  • Medical Degree
    MBBS, Imperial College London
  • Professional Registration
    GMC Registered Medical Practitioner
  • Specialization
    General Practice (GP) Certification
  • Advanced Training
    Dermatology & Aesthetic Medicine Specialization

About Rejuva London

Established in on prestigious Harley Street,
Rejuva London has served over 20,000 clients through our doctor-led approach to aesthetic medicine.

Aesthetic Clinic London:
15 Harley Street
London
W1G 9QQ
United Kingdom

20,000+Clients Treated
6+Years of Excellence
100%Doctor-Led

Treatment Philosophy:

“My approach to aesthetic medicine centers on enhancing natural beauty while prioritizing patient safety.
Every treatment at Rejuva London is tailored to the individual, combining medical expertise with artistic
vision to achieve results that look naturally refreshed, never overdone.”
– Dr. Kristy Lau

Professional Memberships & Affiliations:

  • General Medical Council (GMC)
  • British College of Aesthetic Medicine
  • British Association of Cosmetic Doctors

Consult with Dr. Lau in Aesthetic Clinic in London:

Experience the Rejuva London difference with a personalized consultation