Rejuva London Harley Street
Rejuva London Harley Street
nasolabial fold fillers smile lines treatment

Nasolabial Fold Fillers: Smooth Smile Lines & Marionette Lines

Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Please consult with a qualified medical professional for personalized assessment and treatment recommendations.

Medical Review: This article has been medically reviewed and approved by Dr. Kristy Lau.

Mar 6, 2026

Mar 6, 2026

Nasolabial Fold Fillers: A Doctor-Led Guide

Nasolabial Fold Fillers offer a refined solution for smile and marionette lines. This guide explains the treatment benefits and procedure, while also providing unique insight into advanced regenerative approaches. We discuss how bio-stimulators encourage long-term collagen production for truly restorative results. Discover the value of a comprehensive, doctor-led consultation process and understand the connection between Harley Street and unparalleled medical excellence, ensuring your complete peace of mind before treatment.

At Rejuva London, winner of the Best Anti-Ageing Clinic London 2025 award, your care is our highest priority. All consultations and treatments are personally conducted by our Medical Director, Dr. Kristy Lau. Her doctor-led philosophy ensures every procedure is founded on safety, aiming for restorative and elegantly natural outcomes. Our prestigious Harley Street location reflects our unwavering commitment to clinical excellence and patient safety in every aspect of your facial rejuvenation journey.

To begin your journey towards restored confidence and natural beauty, book your consultation at our Harley Street clinic today.

Table of Contents

What Are Nasolabial Folds and Marionette Lines?

Nasolabial folds, often called ‘smile lines’ or ‘laugh lines’, are the creases that run from the sides of the nose to the corners of the mouth. Marionette lines extend downwards from the corners of the mouth to the jawline. While a natural part of facial anatomy, they can deepen over time, creating a tired or aged appearance.

The primary cause of prominent nasolabial folds and marionette lines is the natural ageing process. As we age, our skin’s production of collagen and elastin—the proteins responsible for firmness and elasticity—declines significantly. Simultaneously, we experience a loss and redistribution of facial fat, particularly in the mid-face and cheek area. This loss of structural support causes the skin to sag downwards, making these facial wrinkles more pronounced. Other contributing factors that can accelerate this process include genetics, significant sun exposure, lifestyle choices like smoking, and repetitive facial expressions. At Rejuva London, we use expertly administered Nasolabial Fold Fillers to restore this lost volume, soften the appearance of these lines, and rejuvenate the lower face for a naturally refreshed and youthful look.

How Do Dermal Fillers Restore and Regenerate Volume?

At Rejuva London, our philosophy extends beyond simply filling lines; we focus on genuine facial restoration. Dermal fillers are not just about adding volume but about strategically replenishing the face’s natural architecture. The most common fillers are composed of hyaluronic acid (HA), a substance that occurs naturally in the body, which draws moisture to the area, providing immediate support and hydration to lift and smooth the skin.

However, our advanced, doctor-led approach embraces the next generation of aesthetic treatments: bio-stimulatory fillers. Unlike traditional HA fillers that primarily provide volume, bio-stimulators such as Sculptra and Radiesse work by activating your body’s own regenerative capabilities. When injected, these products create a scaffold beneath the skin, triggering a process called neocollagenesis—the production of new, strong collagen and elastin fibres. This means that over the weeks and months following your treatment, your skin rebuilds its own youthful structure from within. The result is not only the softening of facial wrinkles but a progressive and long-lasting improvement in skin quality, texture, and firmness. This regenerative technique, a specialism of Dr. Kristy Lau, ensures results are exceptionally natural, restorative, and align with our commitment to subtle, elegant enhancements rather than artificial-looking changes.

Are You a Suitable Candidate for Smile Line Fillers?

An effective smile lines treatment is suitable for a wide range of individuals seeking to address the signs of ageing in the lower and mid-face. You may be an ideal candidate if you have noticed that your smile lines or nasolabial folds are visible even when your face is at rest, contributing to a tired or sad appearance. This treatment is highly effective for those experiencing mild to moderate volume loss in the cheeks, which can exacerbate the depth of these folds.

Ideal candidates are adults in good overall health who have realistic expectations about the outcomes of a non-surgical procedure. They are looking for a significant, yet natural-looking improvement rather than a complete transformation. This treatment is perfect for those who wish to achieve a refreshed, more youthful look without the downtime and risks associated with surgery. During your comprehensive consultation with Dr. Kristy Lau, she will conduct a holistic facial assessment to determine if nasolabial fold filler is the most appropriate treatment for your unique anatomy and aesthetic goals. In some cases, addressing volume loss in the cheeks first may provide the best and most natural-looking lift, a testament to our doctor-led, patient-first approach.

Your Doctor-Led Treatment Journey on Harley Street

Your safety and comfort are the cornerstones of the Rejuva London experience. Your journey begins with a thorough, one-on-one consultation with our highly esteemed Medical Director, Dr. Kristy Lau. With decades of medical experience and advanced training from Imperial College London, Dr. Lau conducts a meticulous facial analysis, discussing your concerns and aesthetic aspirations to create a bespoke treatment plan tailored precisely to you.

The dermal filler treatment itself is performed with the utmost precision and care in the pristine, clinical environment of our Harley Street clinic. To address the common question, “Are smile line fillers painful?”, we prioritise your comfort at every stage. A topical anaesthetic cream is applied to the treatment area to minimise sensation, and the premium fillers we use contain a local anaesthetic (lidocaine) for a virtually painless experience. Dr. Lau employs advanced injecting techniques, often using a cannula where appropriate, to reduce the risk of bruising and swelling, ensuring a smoother recovery. This doctor-led protocol guarantees that your procedure is not only effective but is performed under the strictest medical safety standards, providing you with the ultimate peace of mind that you are in the hands of a true expert.

What Natural-Looking Results Can I Expect and How Long Do They Last?

The goal of our anti-aging fillers is to restore and refresh, not to alter your natural appearance. Immediately following the treatment, you will notice a visible softening of the nasolabial folds and a subtle lift in the mid-face. The results are designed to be elegant and harmonious with your facial features, leaving you looking rested and rejuvenated, as if you’ve just returned from a relaxing holiday. Friends and family may notice you look well, but the treatment itself will be imperceptible.

The longevity of your results depends on several factors, including the type of filler used, your individual metabolism, and lifestyle. At Rejuva London, we use only premium, FDA-approved dermal fillers renowned for their quality and durability. You can typically expect the beautiful, natural-looking results to last between 9 to 18 months. For those who opt for bio-stimulatory fillers, the collagen-building effects can provide a longer-lasting improvement in skin quality. Dr. Lau will recommend a personalised maintenance plan during your consultation to ensure you enjoy your refreshed appearance for as long as possible. To learn more about our filler treatments and the specific products we use, please visit our main treatment page.

Filler Longevity Comparison

Filler TypePrimary ComponentTypical LongevityBest For
Standard Hyaluronic Acid (HA)Hyaluronic Acid9 – 12 MonthsDirect volume replacement and line softening
Advanced HA (Vycross Tech)Cross-linked Hyaluronic Acid12 – 18 MonthsDeeper folds requiring structure and lift
Bio-Stimulatory FillersCaHA or PLLA18 – 24+ MonthsLong-term collagen stimulation and skin firming

Risks & Aftercare: Ensuring a Safe and Smooth Recovery

While nasolabial fold filler is a minimally invasive procedure with an excellent safety profile when performed by a qualified medical doctor, it is important to be aware of potential side effects. The most common reactions are temporary and mild, typically resolving within a few days. These include redness, swelling, tenderness, and bruising at the injection sites. Lumps or bumps may occasionally be felt under the skin, which usually smooth out on their own over a week or two.

More serious complications, though very rare, can include infection, allergic reaction, or vascular occlusion (where filler is inadvertently injected into a blood vessel). The extensive anatomical knowledge and precise injection techniques of an expert like Dr. Kristy Lau significantly mitigate these risks. To ensure a smooth recovery and optimal results, we provide comprehensive aftercare instructions. We advise patients to avoid strenuous exercise, excessive sun or heat exposure, and alcohol for 24-48 hours post-treatment. It is also recommended to avoid applying firm pressure to the treated area for the first few days. Adhering to this guidance will help minimise swelling and allow the filler to settle perfectly into place, ensuring a beautiful, safe outcome.


Why Choose Rejuva London for Your Filler Treatment?

Choosing a clinic for facial injectables is a significant decision. At Rejuva London, you are selecting a standard of care that is unparalleled. Situated in the world-renowned Harley Street medical district, our clinic embodies the pinnacle of medical excellence and patient safety. Our distinction as the “Best Anti-Ageing Clinic London 2025” is a testament to our unwavering commitment to delivering superior, natural-looking results within a framework of clinical rigour.

Every aspect of your facial rejuvenation is overseen by our esteemed Medical Director, Dr. Kristy Lau. Unlike many other clinics, all injectable treatments at Rejuva London are performed exclusively by our expert doctor, never by a therapist or nurse. This doctor-led promise ensures you benefit from the highest level of anatomical expertise and aesthetic artistry, minimising risks and maximising outcomes. Our philosophy is rooted in restorative and regenerative medicine; we focus on enhancing your unique beauty by stimulating your skin’s own vitality. For a premium, reassuring, and clinically authoritative experience, entrust your care to Dr. Kristy Lau and the award-winning team at our Harley Street clinic.

Book Your Expert Consultation with Dr. Kristy Lau Today

The first step towards refreshing your appearance and softening smile lines is a comprehensive, personal consultation. This dedicated time with Dr. Kristy Lau allows for a complete assessment of your facial anatomy, a discussion of your aesthetic goals, and the creation of a bespoke treatment plan that respects and enhances your natural beauty. Experience the reassurance and clinical excellence of a truly doctor-led aesthetic journey. We invite you to begin your transformation in the discreet, elegant environment of our prestigious clinic. Contact our Harley Street clinic today to schedule your appointment and explore how we can help you achieve a beautifully refreshed and confident look.

To discover a personalised, natural approach to aesthetics, book a consultation with our expert medical team at Rejuva London’s award-winning Harley Street clinic.

Your Questions Answered: Nasolabial Fold Filler FAQs

Do dermal fillers work for smile lines?

Yes, dermal fillers are exceptionally effective for treating smile lines, also known as nasolabial folds. By precisely restoring lost volume with a sophisticated hyaluronic acid-based gel, fillers can soften the crease, smooth the surrounding skin, and create a more refreshed, natural-looking facial contour.

A successful outcome relies on a detailed facial assessment by an experienced medical professional to determine the optimal filler type and placement for your unique anatomy.

Are nasolabial fold filler treatments painful?

Most patients report minimal discomfort during nasolabial fold filler treatments. At our Harley Street clinic, Dr. Kristy Lau uses premium dermal fillers that contain a local anaesthetic (lidocaine) to enhance your comfort, and a topical numbing cream is applied beforehand to ensure the procedure is as gentle as possible.

You may feel a slight pinching sensation upon injection, but the procedure is generally very well-tolerated.

What type of filler is best for nasolabial folds?

The most suitable fillers for nasolabial folds are typically based on hyaluronic acid (HA), a substance that naturally provides hydration and volume in the skin. For certain patients, Dr. Lau may recommend collagen-stimulating fillers (bio-stimulators) to encourage long-term skin regeneration and structural support.

The choice is entirely bespoke, tailored to your skin quality and aesthetic goals during your comprehensive, doctor-led consultation.

Is there any downtime after the treatment?

There is typically no significant downtime following nasolabial fold filler treatment, allowing most patients to resume their normal activities immediately. You may experience some mild, temporary redness, swelling, or bruising at the injection sites, which usually resolves within a few days.

We provide all patients with thorough aftercare instructions to minimise these effects and ensure a smooth, swift recovery.

Can fillers help prevent marionette lines from forming?

While fillers primarily treat existing lines, a strategic and holistic treatment plan can help prevent the worsening of marionette lines and other facial wrinkles. By supporting the mid-face structure and stimulating your own collagen, treatments can proactively maintain a youthful contour and delay the formation of deeper folds.

This preventative approach is a cornerstone of our doctor-led philosophy, focusing on long-term, natural-looking rejuvenation.

How much do nasolabial fold fillers cost in London?

The cost of nasolabial fold filler treatment is tailored to each individual, as it depends on the specific type and volume of product required to achieve your desired result. At our Harley Street clinic, a clear and transparent pricing structure will be discussed during your initial consultation with Dr. Lau.

This ensures your investment is precisely aligned with a bespoke treatment plan designed to meet your unique aesthetic goals.

Dr. Kristy Lau, Medical Director of Rejuva London

Dr. Kristy Lau

Medical Director & Founder

Aesthetic Clinic London

MBBS Imperial College London
GMC Registered
30+ Years Medical Experience

Dr. Kristy Lau is the founder and Medical Director of

Rejuva London Clinic
, an

Imperial College London

graduate with over 10 years of comprehensive medical expertise. Specializing in dermatology and medical aesthetics, Dr. Lau combines rigorous medical training with advanced aesthetic technologies to deliver personalized, natural-looking treatments.

At Rejuva London’s prestigious Harley Street location, Dr. Lau ensures all procedures are performed exclusively by highly experienced doctors, maintaining the highest standards of safety and excellence in aesthetic medicine. Her doctor-led approach has successfully treated over 20,000 clients since establishing the clinic in 2018.

Medical Specializations:

Injectable Treatments
  • Anti-wrinkle Injections (Botox)
  • Dermal Fillers
  • Facial Contouring
Advanced Technologies
  • Picosure Pro Laser
  • Thermage RF
  • Ultherapy
Medical Dermatology
  • Skin Health Assessment
  • Medical Aesthetics
  • Laser Skin Treatments

Professional Qualifications & Credentials:

  • Medical Degree
    MBBS, Imperial College London
  • Professional Registration
    GMC Registered Medical Practitioner
  • Specialization
    General Practice (GP) Certification
  • Advanced Training
    Dermatology & Aesthetic Medicine Specialization

About Rejuva London

Established in on prestigious Harley Street,
Rejuva London has served over 20,000 clients through our doctor-led approach to aesthetic medicine.

Aesthetic Clinic London:
15 Harley Street
London
W1G 9QQ
United Kingdom

20,000+Clients Treated
6+Years of Excellence
100%Doctor-Led

Treatment Philosophy:

“My approach to aesthetic medicine centers on enhancing natural beauty while prioritizing patient safety.
Every treatment at Rejuva London is tailored to the individual, combining medical expertise with artistic
vision to achieve results that look naturally refreshed, never overdone.”
– Dr. Kristy Lau

Professional Memberships & Affiliations:

  • General Medical Council (GMC)
  • British College of Aesthetic Medicine
  • British Association of Cosmetic Doctors

Consult with Dr. Lau in Aesthetic Clinic in London:

Experience the Rejuva London difference with a personalized consultation