Rejuva London Harley Street
Rejuva London Harley Street
Treating Melasma Pigmentation With Picosure Pro

Treating Melasma and Pigmentation with PicoSure Pro Laser

Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Please consult with a qualified medical professional for personalized assessment and treatment recommendations.

Medical Review: This article has been medically reviewed and approved by Dr. Kristy Lau.

May 24, 2026

May 24, 2026

Picosure Pro for Melasma: Advanced Treatment for Pigmentation

Picosure pro for melasma provides an advanced, non-thermal solution for persistent hyperpigmentation. This picosecond laser therapy utilizes PressureWave technology to shatter melanin into tiny particles, which the body naturally clears. Unlike traditional heat-based lasers, PicoSure Pro minimizes thermal impact, significantly reducing the risk of post-inflammatory hyperpigmentation (PIH) and making it ideal for heat-sensitive conditions like hormonal pigmentation. It effectively addresses both epidermal melasma and dermal melasma, offering a safer and more precise approach to achieving a clearer, more even complexion.

Rejuva London, a doctor-led clinic on Harley Street, specializes in advanced laser technologies like PicoSure Pro. Their expertise ensures precise, evidence-based treatment for complex skin conditions such as melasma, prioritizing patient safety and optimal outcomes.

To explore your options, contact us to schedule your consultation. You can also reach us via: Book an Anti-Ageing Skin Assessment

Picosure pro for melasma offers an advanced approach for stubborn hyperpigmentation. Melasma, a skin condition causing dark patches, is often exacerbated by hormonal changes and sun exposure, making it difficult to treat. This picosecond laser technology, available at Rejuva London, targets and clears unwanted pigment without the high thermal energy of traditional lasers, resulting in a clearer, more even-toned complexion.

What is Melasma and Why is it So Challenging to Treat?

Melasma is a chronic skin condition characterized by brown or greyish-brown patches of pigmentation, typically on the face. It occurs when melanocytes, the skin’s pigment-producing cells, become overactive. This condition is challenging because it is triggered by hormones, sun exposure, and heat, and it can exist at different depths within the skin—as epidermal (superficial) or dermal (deep) melasma. Traditional laser treatments that rely on heat can stimulate these sensitive melanocytes, often leading to a worsening of the condition known as rebound hyperpigmentation.

Understanding Hormonal Pigmentation and Its Triggers

Melasma has a strong connection to fluctuations in oestrogen and progesterone, which is why it is often called hormonal pigmentation. It commonly affects women during pregnancy (chloasma or “the mask of pregnancy”) or those using oral contraceptives. The condition is not exclusively hormonal. Environmental factors, especially ultraviolet (UV) radiation from the sun and visible light, are significant triggers that stimulate pigment production. This interplay of internal and external factors makes melasma a persistent condition that requires a careful treatment approach.

How Does PicoSure Pro Revolutionize Melasma Treatment?

The PicoSure Pro laser by Cynosure is an advancement in treating pigmentation disorders. Its innovation is its pulse duration. It delivers energy in picoseconds—trillionths of a second—which is 100 times shorter than the nanosecond pulses of older Q-switched lasers. This ultra-short pulse creates a photomechanical or photoacoustic effect using PressureWave technology. Instead of generating heat to destroy pigment, it creates a pressure wave that shatters melanin into minuscule, dust-like particles. The body’s lymphatic system then clears these tiny particles.

The Science Behind Picosecond Laser Therapy for Pigment

The primary advantage of this photoacoustic mechanism is the minimal thermal impact on surrounding skin. By avoiding excessive heat build-up, picosecond laser therapy significantly reduces the risk of triggering an inflammatory response. This is critical for melasma, as inflammation can stimulate melanocytes and lead to post-inflammatory hyperpigmentation (PIH)—a common side effect of heat-based treatments. This makes PicoSure Pro a safer option for managing heat-sensitive conditions like melasma.

PicoSure Pro vs. Other Lasers: A Comparison for Melasma

What is Melasma and Why is it So Challenging to Treat? — Treating Melasma and Pigmentation with PicoSure Pro Laser

Why Choose Rejuva London for Your PicoSure Pro Melasma Treatment?

Managing melasma requires medical expertise, precise technology, and a personalized strategy. At Rejuva London, at 15 Harley Street, your treatment is overseen by a qualified medical doctor. This doctor-led approach ensures your skin is in safe, capable hands. Our founder, Dr. Kristy Lau, a graduate of Imperial College London, has extensive experience in laser technologies and dermatological conditions, prioritizing patient safety and optimal outcomes.

The Rejuva London Doctor-Led Difference for Pigmentation

A doctor-only protocol is non-negotiable for treating melasma. A medical doctor can accurately diagnose the type and depth of your pigmentation, differentiate it from other conditions, and set laser parameters with precision. This expertise is crucial for navigating the fine line between improving and aggravating melasma. Our recognition as the ‘Best Anti-Ageing Clinic – London’ by the GHP Global Excellence Awards 2025 reflects our commitment to clinical quality and patient satisfaction.

Personalized Treatment with Advanced VISIA Skin Analysis

Before any treatment, we use advanced VISIA Skin Analysis. This technology provides a multi-spectral assessment of your skin, revealing objective data on pigmentation, sun damage, and inflammation beneath the surface. It allows our doctors to visualize the extent of epidermal and dermal melasma, track your progress with quantifiable metrics, and tailor the PicoSure Pro treatment plan to your skin’s needs for effective hormonal pigmentation treatment.

What to Expect: Your PicoSure Pro Melasma Journey at Rejuva London

Your treatment begins with a consultation and VISIA skin analysis with one of our doctors. A typical melasma treatment plan involves 3-6 sessions, scheduled 2-4 weeks apart. During the procedure, you may feel a sensation like a light snapping of a rubber band against the skin, which is generally well-tolerated. Each session lasts 15-30 minutes, depending on the treatment area size. There is minimal downtime; most patients experience only mild redness for a few hours post-treatment.

Preparing for Your PicoSure Pro Session and Aftercare Essentials

To prepare, avoid sun exposure and discontinue retinoids or other photosensitizing skincare products for at least one week before your session. Aftercare is critical. Strict use of a broad-spectrum SPF 50+ sunscreen is non-negotiable to protect the skin and prevent re-pigmentation. Your doctor will also recommend a gentle skincare regimen and may suggest topical tyrosinase inhibitors—ingredients that suppress pigment production—to maintain results and manage melasma’s chronic nature.

Understanding Laser Toning and Expected Results

Melasma treatment with PicoSure Pro is a form of laser toning with gradual results. The shattered pigment is not instantly removed; it is cleared by your body’s natural processes over the following weeks. Patients typically notice a gradual fading of pigmented patches and an overall brighter complexion. Have realistic expectations: the goal is significant improvement and long-term management, not a permanent cure, as melasma can recur with triggers.

Why Choose Rejuva London for Your PicoSure Pro Melasma Treatment? — Treating Melasma and Pigmentation with PicoSure Pro Laser

Can PicoSure Pro Effectively Treat Dermal Melasma and PIH?

A great challenge in pigmentation treatment is dermal melasma, where pigment is located deep in the skin’s dermal layer. This depth makes it resistant to many topical treatments and superficial lasers. The PicoSure Pro’s 755nm wavelength is effective at targeting melanin, and its photoacoustic mechanism allows energy to penetrate deeply and shatter dermal pigment without causing excessive thermal damage to the overlying epidermis. This makes it a suitable tool for this stubborn form of melasma.

Targeting Stubborn Dermal Melasma with Precision

The precision of picosecond laser therapy allows for targeted destruction of deep pigment particles while preserving surrounding healthy tissue. This selective action is crucial for avoiding complications and achieving clearance of dermal melasma. The treatment helps break down deep-seated pigment, allowing the body to clear it and reveal a more uniform skin tone.

Preventing and Treating Post-Inflammatory Hyperpigmentation (PIH)

Post-inflammatory hyperpigmentation (PIH) is the skin’s response to injury or inflammation, resulting in dark spots. It is a significant concern, especially for individuals with darker skin tones. Because the PicoSure Pro operates with minimal heat, it significantly lowers the risk of inducing the inflammation that causes PIH. Its gentle yet effective pigment-shattering ability makes it an excellent treatment for clearing existing PIH from acne, skin trauma, or other laser procedures. This dual capability makes it a safe and effective treatment for a wide range of pigmentation concerns.

Ready for Clearer Skin? Book Your PicoSure Pro Consultation

A medical-led approach is key to achieving clear, lasting, and safe results for melasma or other stubborn pigmentation. At Rejuva London, we combine advanced technology with clinical expertise to create a personalized treatment plan. Schedule a consultation with our medical team to start toward a brighter, more even complexion.

Your Journey to a Brighter Complexion Starts Here

Understand your pigmentation with a VISIA skin analysis and a discussion with our doctor. We provide safe, effective, and natural-looking results in a clinical, patient-focused environment. Book an Anti-Ageing Skin Assessment today to discover how the PicoSure Pro laser can help you manage your skin.

Conclusion

Treating melasma effectively requires a technology that targets pigment without aggravating the condition with excessive heat. The PicoSure Pro laser, with its picosecond PressureWave technology, shatters pigment through a photoacoustic effect. This makes it a superior and safer option for managing both dermal and epidermal melasma, as well as post-inflammatory hyperpigmentation. At a doctor-led clinic like Rejuva London, this technology is paired with expert diagnosis and personalized plans, ensuring safety and efficacy. To learn more about our approach to skin rejuvenation, contact us or Book an Anti-Ageing Skin Assessment to begin your treatment.

Frequently Asked Questions

Why is PicoSure Pro considered a superior laser for melasma?

PicoSure Pro is highly effective because its picosecond pulse duration shatters pigment via a photoacoustic (sound) effect, not high heat. This unique mechanism avoids the thermal trigger that can often worsen melasma, making it a safer and more reliable option under medical supervision. This makes the picosure pro for melasma treatment a breakthrough for this challenging condition.

Can PicoSure Pro for melasma treat deeper, dermal pigmentation?

Yes, the PicoSure Pro laser is uniquely effective at treating both superficial (epidermal) and deep (dermal) melasma. Its 755nm wavelength is highly absorbed by melanin, and the picosecond pulse shatters deep pigment particles without damaging surrounding tissue. This allows the body’s lymphatic system to clear the fragmented pigment over time.

How does Rejuva London ensure the safety of PicoSure Pro for melasma?

At Rejuva London, our doctor-only protocol ensures the highest safety standards for PicoSure Pro for melasma treatments. We begin with a thorough VISIA skin analysis and Fitzpatrick skin typing to determine the precise, safe energy settings for your skin. This data-driven approach, managed by our expert doctors, minimises the risk of post-inflammatory hyperpigmentation.

What is the recovery process like after a PicoSure Pro melasma treatment?

The recovery after a PicoSure Pro session for pigmentation is minimal. Patients typically experience only mild redness for a few hours, with no significant downtime, allowing an immediate return to normal activities. Strict sun avoidance and adherence to a prescribed medical-grade skincare regimen are crucial for protecting your results.

How many treatments are required for PicoSure Pro for melasma to show results?

While individual results vary, most patients see a noticeable improvement in their skin tone after 2-3 sessions of PicoSure Pro for melasma. For optimal clearance of stubborn pigmentation, a full course of 3-5 treatments, spaced 4-6 weeks apart, is typically recommended. Our doctors will create a personalised treatment plan based on your specific condition.

How can I find out if I am a suitable candidate for this laser treatment?

The best way to determine your suitability is to schedule a comprehensive skin assessment with one of our doctors. During this consultation, we will use advanced diagnostics like VISIA analysis to evaluate your melasma and create a tailored treatment plan. You can book an anti-ageing skin assessment on our website to begin your journey to clearer skin.

Dr. Kristy Lau, Medical Director of Rejuva London

Dr. Kristy Lau

Medical Director & Founder

Aesthetic Clinic London

MBBS Imperial College London
GMC Registered
30+ Years Medical Experience

Dr. Kristy Lau is the founder and Medical Director of

Rejuva London Clinic
, an

Imperial College London

graduate with over 10 years of comprehensive medical expertise. Specializing in dermatology and medical aesthetics, Dr. Lau combines rigorous medical training with advanced aesthetic technologies to deliver personalized, natural-looking treatments.

At Rejuva London’s prestigious Harley Street location, Dr. Lau ensures all procedures are performed exclusively by highly experienced doctors, maintaining the highest standards of safety and excellence in aesthetic medicine. Her doctor-led approach has successfully treated over 20,000 clients since establishing the clinic in 2018.

Medical Specializations:

Injectable Treatments
  • Anti-wrinkle Injections (Botox)
  • Dermal Fillers
  • Facial Contouring
Advanced Technologies
  • Picosure Pro Laser
  • Thermage RF
  • Ultherapy
Medical Dermatology
  • Skin Health Assessment
  • Medical Aesthetics
  • Laser Skin Treatments

Professional Qualifications & Credentials:

  • Medical Degree
    MBBS, Imperial College London
  • Professional Registration
    GMC Registered Medical Practitioner
  • Specialization
    General Practice (GP) Certification
  • Advanced Training
    Dermatology & Aesthetic Medicine Specialization

About Rejuva London

Established in on prestigious Harley Street,
Rejuva London has served over 20,000 clients through our doctor-led approach to aesthetic medicine.

Aesthetic Clinic London:
15 Harley Street
London
W1G 9QQ
United Kingdom

20,000+Clients Treated
6+Years of Excellence
100%Doctor-Led

Treatment Philosophy:

“My approach to aesthetic medicine centers on enhancing natural beauty while prioritizing patient safety.
Every treatment at Rejuva London is tailored to the individual, combining medical expertise with artistic
vision to achieve results that look naturally refreshed, never overdone.”
– Dr. Kristy Lau

Professional Memberships & Affiliations:

  • General Medical Council (GMC)
  • British College of Aesthetic Medicine
  • British Association of Cosmetic Doctors

Consult with Dr. Lau in Aesthetic Clinic in London:

Experience the Rejuva London difference with a personalized consultation