Profhilo London: Revolutionary Hyaluronic Acid Bio-Remodelling

Profhilo Treatment: Natural Skin Rejuvenation Without Surgery

If you’re concerned about skin laxity, dehydration, and the visible signs of ageing but hesitant about invasive procedures, Profhilo offers a revolutionary solution. This award-winning treatment addresses the underlying causes of ageing skin—not just the symptoms—providing natural-looking rejuvenation without changing your facial features.

Profhilo is a unique hyaluronic acid bio-remodelling treatment that stimulates your skin’s natural collagen and elastin production. Unlike traditional fillers, it doesn’t add volume but instead improves skin quality from within, addressing crepey texture, fine lines, and loss of firmness with just 10 small injections across two sessions.

Recovery is minimal—you’ll experience small, temporary bumps at injection sites that resolve within 24 hours, allowing you to return to normal activities almost immediately. Most patients see initial improvements within 10-14 days, with optimal results appearing 2-3 months after completing the two-session protocol.

As a doctor-led clinic, all Profhilo treatments at Rejuva London are personally performed by Dr. Daniel Hunt, ensuring precise application and natural-looking results that enhance your own features rather than creating an artificial appearance.

Discover if Profhilo is right for your skin concerns by booking a personalised consultation. We’ll assess your unique needs and create a tailored treatment plan to help you achieve naturally rejuvenated, healthier-looking skin.

Table of Contents

• Understanding Profhilo: The Next Generation of Skin Remodelling
• How Does Profhilo Treatment Differ From Traditional Fillers?
• The Science Behind Hyaluronic Acid Bio-Remodelling
• Key Benefits of Profhilo for Aging and Dehydrated Skin
• What Areas Can Be Treated With Profhilo in London?
• Your Profhilo Journey: Treatment Process and Timeline
• Maximizing Your Results: Profhilo Aftercare and Maintenance
• Finding Expert Profhilo Treatment in London

Understanding Profhilo: The Next Generation of Skin Remodelling

As a doctor with over 30 years of medical experience, I’ve witnessed numerous advancements in aesthetic medicine, but few have impressed me as much as Profhilo. This revolutionary bio-remodelling treatment represents a paradigm shift in how we approach skin rejuvenation at our Harley Street clinic.

Profhilo is not simply another dermal filler or skin booster—it’s a unique hyaluronic acid treatment specifically designed to address skin laxity and improve tissue quality from within. What makes it truly exceptional is its high concentration of ultrapure hyaluronic acid (64mg/2ml) with distinctive rheological properties that allow it to flow beneath the skin, creating a natural scaffolding effect.

Think of Profhilo as a liquid moisturiser that works beneath your skin’s surface. Unlike traditional treatments that target specific lines or wrinkles, Profhilo distributes evenly across tissue planes, stimulating four types of collagen and elastin production while deeply hydrating from within. This results in what we call the “Profhilo glow”—skin that appears naturally rejuvenated, firmer, and more radiant.

At Rejuva London, I personally administer all Profhilo treatments, ensuring each patient receives the precise technique required for optimal results. The treatment involves just five injection points on each side of the face (the “BAP technique”), making it relatively comfortable with minimal downtime—a significant advantage for my busy London patients.

How Does Profhilo Treatment Differ From Traditional Fillers?

One of the most common questions my patients ask is how Profhilo differs from the dermal fillers they’re familiar with. The distinction is fundamental and affects everything from the treatment approach to the results you can expect.

Traditional dermal fillers are designed to add volume and structure to specific areas—think of them as sculptural tools that reshape and contour. They remain in place where injected, creating definition in areas like cheeks, lips, or nasolabial folds. In contrast, Profhilo doesn’t add volume or alter facial structure; instead, it improves skin quality throughout the treated area.

At Rejuva London, I often recommend Profhilo as a foundational treatment to improve overall skin quality before considering more targeted interventions. Many of my patients are delighted to discover that after completing their Profhilo course, they require less filler or sometimes none at all, as their skin’s natural appearance has improved so significantly.

For those seeking the most natural-looking results, Profhilo offers the perfect solution—it enhances your skin’s inherent qualities rather than changing your appearance. This aligns perfectly with our clinic philosophy of subtle, doctor-led treatments that respect your natural features.

The Science Behind Hyaluronic Acid Bio-Remodelling

The science behind Profhilo’s effectiveness lies in its unique formulation and how it interacts with your skin’s biology. As a medical professional trained at Imperial College London, I find the technology behind this treatment particularly fascinating.

Profhilo contains one of the highest concentrations of hyaluronic acid (HA) available in any injectable treatment—64mg/2ml. What makes it revolutionary, however, is not just the quantity but the quality and structure of this hyaluronic acid. The manufacturers have developed a patented NAHYCO® technology that creates a hybrid cooperative complex of high and low molecular weight HA chains.

Think of it as creating a perfect balance between stability and fluidity. The high molecular weight HA (H-HA) provides structural support and longevity, while the low molecular weight HA (L-HA) offers superior spreadability and bioactivity. When injected, this hybrid complex creates a honeycomb-like network beneath the skin that gradually releases HA over approximately 28 days.

This slow-release mechanism triggers several biological processes:

• Stimulation of fibroblasts—the cells responsible for collagen and elastin production
• Activation of adipocytes (fat cells) to improve tissue volume and quality
• Enhancement of keratinocyte viability for improved skin surface quality
• Increased production of type I, III, IV, and VII collagen
• Improved extracellular matrix quality and hydration

The result is what dermatologists call “bio-remodelling”—a comprehensive improvement in skin quality that addresses multiple signs of ageing simultaneously. Unlike treatments that simply fill wrinkles or add volume, Profhilo works with your body’s natural processes to regenerate tissue from within.

At Rejuva London, our doctor-led approach ensures we stay at the forefront of such scientific advancements, offering treatments that deliver genuine physiological benefits rather than temporary cosmetic fixes.

Key Benefits of Profhilo for Aging and Dehydrated Skin

After treating thousands of patients at our Harley Street clinic, I’ve observed consistent and impressive benefits from Profhilo treatments. The results speak for themselves, but understanding exactly what Profhilo can achieve helps my patients set realistic expectations.

The primary benefits of Profhilo include:

Deep Hydration

Profhilo delivers intense hydration at a dermal level that topical products simply cannot reach. This addresses the fundamental issue of moisture loss that occurs with age. Patients frequently comment that their skin feels “plumped from within” and that makeup applies more smoothly after treatment.

Improved Skin Elasticity

By stimulating elastin production, Profhilo helps restore the skin’s natural bounce and resilience. This is particularly noticeable in areas prone to sagging, such as the lower face and neck. Many of my patients report their skin feels “tighter” and more supportive after completing their treatment course.

Smoother Skin Texture

The bio-remodelling effect improves overall skin quality, reducing fine lines and creating a more refined texture. This benefit extends beyond wrinkle reduction to address overall skin health, creating what many describe as a “filter-like” effect in real life.

Natural-Looking Radiance

Perhaps the most commented-on benefit is the natural luminosity Profhilo imparts. Unlike makeup or other treatments that can look artificial, Profhilo enhances your skin’s natural glow by improving its underlying health and hydration.

Versatility Across Skin Types

Profhilo works effectively across all skin types and ages. It’s particularly beneficial for those in their 30s as a preventative measure, those in their 40s-50s addressing early signs of ageing, and those 60+ looking for significant improvement without surgery.

What makes Profhilo particularly valuable in my clinical practice is its ability to address multiple concerns simultaneously without changing facial features or expressions. It’s the epitome of the “less is more” approach that defines our doctor-led philosophy at Rejuva London.

For patients concerned about looking “done” or unnatural, Profhilo offers the perfect solution—comprehensive improvement without any risk of altering your natural appearance. It’s rejuvenation in its truest sense: enhancing what’s already there rather than adding something foreign.

What Areas Can Be Treated With Profhilo in London?

While Profhilo initially gained popularity as a facial treatment, its versatility extends well beyond the face. At Rejuva London, I regularly treat multiple areas with this revolutionary bio-remodelling solution, addressing concerns from head to toe.

Face

The face remains the most requested area for Profhilo treatment. Using the BAP (Bio Aesthetic Points) technique, I place five strategic injections on each side of the face. These carefully selected points allow the product to flow along tissue planes, reaching areas prone to skin laxity such as the nasolabial folds, marionette lines, and cheeks. The result is comprehensive facial rejuvenation with minimal injection points.

Neck

The neck shows signs of ageing earlier than many other areas due to its thinner skin and constant movement. Profhilo is exceptionally effective here, addressing the “crepe paper” texture many of my London patients find concerning. Treatment involves a series of small injections across the anterior neck, resulting in noticeable improvement in skin quality and reduction in horizontal neck lines.

Décolletage

Sun damage and natural ageing often manifest prominently on the chest area. Profhilo can significantly improve skin texture, reduce fine lines, and restore hydration to this delicate zone. Many of my female patients particularly appreciate this treatment before special occasions or summer months when this area is more exposed.

Hands

Our hands can betray our age perhaps more than any other body part. Profhilo hand treatments address volume loss, prominent veins, and crepey skin texture. The treatment is quick and comfortable, with results that restore a more youthful appearance to this highly visible area.

Arms

Inner arm laxity responds remarkably well to Profhilo. The treatment helps improve skin quality and tightness in an area that’s resistant to improvement through exercise alone.

Knees

Knee skin often becomes crepey and loose with age. Profhilo can significantly improve the appearance of the skin around the knees, creating a smoother, more youthful look.

At our Harley Street clinic, I often recommend combination treatments for optimal results. For instance, Profhilo works synergistically with skin boosters for patients requiring additional targeted hydration or with technologies like Thermage for enhanced skin tightening.

Your Profhilo Journey: Treatment Process and Timeline

At Rejuva London, your Profhilo journey begins with a thorough consultation where I personally assess your skin quality, discuss your concerns, and determine if Profhilo is the right treatment for you. This doctor-led approach ensures you receive tailored advice based on medical expertise rather than a one-size-fits-all recommendation.

The Standard Profhilo Protocol

The standard Profhilo treatment involves two sessions spaced 4 weeks apart. This protocol has been clinically proven to deliver optimal bio-remodelling results. Here’s what to expect:

First Treatment Session

After cleansing the skin, I apply a topical numbing cream to ensure your comfort. Using the BAP technique, I administer five precise injections on each side of the face (or the appropriate technique for other treatment areas). The entire procedure takes approximately 20-30 minutes. You’ll notice some small bumps at the injection sites, which typically subside within 24 hours.

The 4-Week Interval

During this period, Profhilo begins its bio-stimulating effects. The hybrid hyaluronic acid complex slowly diffuses through tissue layers, stimulating fibroblasts and initiating collagen and elastin production. Many patients report seeing initial improvements in skin quality around the 10-14 day mark, though the full remodelling process continues throughout this period.

Second Treatment Session

Four weeks after your initial treatment, you’ll return for your second session. This follows the same procedure as the first but builds upon the foundation already established. This second treatment is crucial for achieving optimal, long-lasting results.

Results Timeline

Understanding the timeline of results helps manage expectations:

• Days 1-3: Initial hydration effects may be visible
• Days 3-10: Any minor swelling or injection site reactions resolve
• Days 10-30: First visible improvements in skin quality and texture
• Days 30-60: Second treatment enhances and deepens these effects
• Months 2-3: Peak results become apparent as collagen remodelling completes
• Months 3-6: Results maintain at optimal levels
• Months 6+: Gradual return to baseline begins

For maintenance, I typically recommend a single booster treatment every 6 months, though this varies based on individual factors such as age, lifestyle, and skin condition. Some of my younger patients maintain results with annual treatments, while those with more mature skin benefit from the standard 6-month maintenance schedule.

Throughout your Profhilo journey at Rejuva London, you’ll benefit from our doctor-led approach, with all treatments performed by myself rather than delegated to non-medical practitioners—ensuring both safety and optimal results.

Maximizing Your Results: Profhilo Aftercare and Maintenance

The success of your Profhilo treatment extends beyond the procedure itself. At Rejuva London, I provide comprehensive aftercare guidance to ensure you achieve and maintain optimal results. Based on my experience treating over 20,000 patients, I’ve developed specific protocols that enhance and extend the benefits of Profhilo bio-remodelling.

Immediate Aftercare (24-48 Hours)

The first 24-48 hours after treatment are crucial for allowing Profhilo to distribute properly and begin its work without interference:

• Avoid touching or massaging the treated areas for at least 24 hours
• Skip makeup application for 24 hours to prevent introducing bacteria to injection sites
• Avoid high-intensity exercise, saunas, steam rooms, and hot baths for 48 hours
• Stay well-hydrated to support the hyaluronic acid’s hydrating effects
• Avoid alcohol consumption for 24 hours as it can increase the risk of bruising and swelling
• Apply SPF 50 if going outdoors, even on cloudy days

Ongoing Skin Support

To complement and enhance your Profhilo results, I recommend the following skincare approach:

• Use gentle, non-stripping cleansers that preserve your skin’s natural barrier
• Incorporate a high-quality hyaluronic acid serum to support surface hydration
• Apply antioxidant serums (particularly vitamin C) in the morning to protect against environmental damage
• Use retinol products in the evening to further support collagen production (unless contraindicated)
• Maintain rigorous sun protection with broad-spectrum SPF 50
• Consider incorporating peptide-rich products to support skin structure

Long-Term Maintenance

Profhilo results typically last 6-9 months, though this varies between individuals. To maintain optimal results, I recommend:

• A single maintenance treatment every 6 months for most patients
• Combination with complementary treatments like Thermage or Ultherapy for enhanced skin tightening if needed
• Annual review of your skin condition to adjust treatment protocols as your skin evolves

Lifestyle Factors

The longevity of your Profhilo results is significantly influenced by lifestyle factors. I advise my patients to:

• Maintain consistent hydration by drinking 2-3 litres of water daily
• Follow an anti-inflammatory diet rich in antioxidants and omega-3 fatty acids
• Limit alcohol consumption and avoid smoking
• Prioritise quality sleep, which is essential for skin regeneration
• Manage stress through regular relaxation practices

At Rejuva London, we view Profhilo not as an isolated treatment but as part of a comprehensive approach to skin health. During your follow-up appointments, I personally assess your results and make tailored recommendations to ensure you continue to enjoy the full benefits of this remarkable bio-remodelling treatment.

Finding Expert Profhilo Treatment in London

When considering Profhilo treatment in London, the provider you choose significantly impacts both your safety and results. As a GMC-registered doctor with over 30 years of medical experience, I cannot overemphasise the importance of seeking treatment from qualified medical professionals.

The Importance of Medical Expertise

Profhilo is a sophisticated medical treatment that requires thorough understanding of facial anatomy and injection techniques. At Rejuva London, our doctor-led only policy means I personally perform all injectable treatments rather than delegating to non-medical practitioners. This approach ensures:

• Precise placement using the BAP technique for optimal product distribution
• Thorough assessment of your skin’s specific needs
• Ability to manage any potential complications immediately
• Customised treatment plans based on medical expertise
• Integration with other treatments when appropriate

Questions to Ask Your Profhilo Provider

Before booking your Profhilo treatment, I recommend asking potential providers:

• Who will perform my treatment? (Is it a doctor, nurse, or non-medical practitioner?)
• What medical qualifications do they hold?
• How many Profhilo treatments have they performed?
• Do they use genuine Profhilo from IBSA Pharma?
• What aftercare and follow-up do they provide?
• How do they handle potential complications?

The Rejuva London Difference

At our Harley Street clinic, we differentiate ourselves through:

• Doctor-led treatments exclusively—I personally perform all injectable procedures
• Comprehensive consultation process to determine suitability
• Custom-tailored treatment plans that may combine Profhilo with complementary procedures
• Premium treatment environment with the latest medical-grade equipment
• Thorough aftercare support and scheduled follow-ups
• Genuine products sourced directly from authorised distributors

Taking the Next Step

If you’re considering Profhilo treatment in London, I invite you to book a consultation at Rejuva London. During this appointment, I’ll assess your skin condition, discuss your aesthetic goals, and determine if Profhilo is the right treatment for you. We’ll create a personalised treatment plan that addresses your specific concerns while ensuring natural-looking results.

With over 20,000 successful treatments performed at our Harley Street clinic, we have the experience and expertise to help you achieve the refreshed, rejuvenated appearance you desire—without compromising on safety or results.

To book your Profhilo consultation, contact our clinic at 020 7637 3208 or visit our website. I look forward to guiding you through your skin rejuvenation journey with this remarkable bio-remodelling treatment.

Frequently Asked Questions

What is Profhilo treatment and how does it differ from other injectables?

Profhilo is a revolutionary bio-remodelling injectable treatment containing one of the highest concentrations of hyaluronic acid (64mg/2ml) available in aesthetic medicine. Unlike traditional fillers that add volume in specific areas, Profhilo flows beneath the skin after injection, creating a scaffolding effect that stimulates collagen and elastin production throughout the treated area. It works as a “liquid moisturiser” that hydrates from within while improving skin quality, elasticity, and firmness without changing facial structure or expression.

How does Profhilo work to rejuvenate the skin?

Profhilo works through a unique bio-remodelling process that stimulates your skin’s natural regenerative capabilities. When injected, its patented NAHYCO® technology (combining high and low molecular weight hyaluronic acid) creates a honeycomb-like network beneath the skin that gradually releases HA over approximately 28 days. This triggers four key biological processes:

• Stimulation of fibroblasts to produce new collagen and elastin
• Activation of adipocytes (fat cells) to improve tissue volume and quality
• Enhancement of keratinocyte viability for better skin surface appearance
• Deep hydration of the extracellular matrix

How long do Profhilo results last and what maintenance is required?

Profhilo results typically last 6-9 months after completing the initial two-treatment protocol. For optimal results, I recommend a standard treatment course of two sessions spaced 4 weeks apart, followed by maintenance treatments every 6 months. Factors affecting longevity include age, skin condition, lifestyle habits, and environmental exposure. Younger patients with good skin quality may maintain results with annual treatments, while those with more mature skin benefit from the standard 6-month maintenance schedule. Supporting your results with proper skincare, hydration, and sun protection will help extend the benefits.

What areas can be treated with Profhilo?

Profhilo can effectively treat multiple areas beyond just the face. The most commonly treated areas include:

• Face – using the BAP (Bio Aesthetic Points) technique with 5 injection points per side
• Neck – particularly effective for horizontal lines and crepey texture
• Décolletage – addressing sun damage and fine lines
• Hands – improving volume loss and prominent veins
• Arms – enhancing skin quality and reducing laxity
• Knees – smoothing crepey skin texture

Each area requires a specific injection technique to ensure optimal product distribution and results.

Are there any side effects or downtime with Profhilo treatment?

Profhilo has minimal side effects and downtime compared to many other aesthetic treatments. Immediately after treatment, you may experience small bumps at injection sites that typically resolve within 24 hours. Common temporary side effects include mild redness, slight swelling, and occasional bruising at injection points. Most patients return to normal activities immediately, though I recommend avoiding intense exercise, heat exposure (saunas, hot baths), alcohol consumption, and makeup application for 24 hours post-treatment. Serious complications are extremely rare when administered by a qualified medical professional, which is why at Rejuva London, all injectable treatments are performed exclusively by myself as a GMC-registered doctor.

Is Profhilo better than dermal fillers for facial rejuvenation?

Profhilo and dermal fillers serve different purposes rather than one being “better” than the other. Profhilo is ideal for improving overall skin quality, hydration, and firmness through bio-remodelling without adding volume or changing facial structure. Dermal fillers, conversely, add targeted volume to specific areas like cheeks or lips and remain where injected. Many of my patients find that after completing a Profhilo course, they require less filler or none at all as their skin quality improves significantly. For comprehensive rejuvenation, I often recommend starting with Profhilo to improve skin quality before considering fillers for any remaining structural concerns—this layered approach creates the most natural-looking results.